Endocrine Abstracts

Background: We have previously shown that systemic levels of the growth hormone (GH) dependent proteins IGF-I and IGFBP-3 are significantly lower in rheumatoid arthritis (RA) patients than in age and sex matched healthy controls.Aim: To investigate whether low levels of systemic IGF-I and IGFBP-3 levels in RA patients are due to GH deficiency or GH insensitivity.Methods: Eight RA patients (6 females, mean plus/minus SD, age 52.5 pl...